Researchers will conduct a clinical trial investigating the safety and anticancer effectiveness of trametinib, a drug to treat companion dogs with aggressive cancers.
Researchers will study metabolic irregularities associated with osteosarcoma that may contribute to disease progression, chemotherapy resistance and cancer spread.
Researchers will investigate the effectiveness of combining radiation therapy with an immune-stimulating agent to help slow the spread of osteosarcoma, the most common bone tumor in dogs.