Developing a New Technique for Limb-Sparing in Dogs with Osteosarcoma

SUMMARY: Researchers will investigate a new surgical limb-sparing technique.

THE PROBLEM: Treatment of appendicular bone tumors in dogs is challenging, and a common treatment method involves aggressive limb amputation. As a desirable alternative to limb amputation treatment, surgical limb sparing also entails challenges even after almost 4 decades, but with the goal of preserving all limbs for bone-tumor affected dogs. Finding a way to improve this technique could help thousands of dogs each year.

THE PROJECT: In attempt to reduce challenges with surgical limb sparing, we seek to develop a method that encourages new patient-derived bone growth to replace the tumorous portion that has been removed and in which the technique may not need to rely permanently on the stabilizing bone plate and screws. With the goal of growing new autogenous bone and removing the implants once this has been accomplished, a new “Repair System” has been developed that allows the dog to grow new viable bone where the segment was removed. We seek to implant this new “Repair System” and monitor the dogs being treated for bone tumors, to document the growth of new bone and report the complications that may be associated with this approach in 8 giant breed dogs.

POTENTIAL IMPACT: If successful, the development of a better technique for limb-sparing surgery could have a profound effect on the health and well-being of dogs suffering from osteosarcoma.