SUMMARY: Researchers will use data from the Golden Retriever Lifetime study cohort to validate the first-ever tool for quantifying chronic stress and predicting stress-associated health risks in dogs. THE PROBLEM...

This study will characterize the expression of toll-like receptors, which activate the immune system, in canine osteosarcoma cells to better determine the biological consequences associated with activating these receptors.

Investigators are assessing the potential for a specific tumor-cell population in canine hemangiosarcoma to sequester drugs within their lysosomes as a novel mechanism of drug resistance.

The goal of this study is to determine new strategies for treating canine mast cell tumors based on the targeting of a DNA-packaging protein called NDY1.

This study investigates how cytogenetic changes in canine osteosarcoma affect the duration of disease-free interval when patients are treated with amputation followed by doxorubicin and non-cytotoxic suramin.

This study will provide a molecular framework for understanding the process of miR-9-driven tumor spread in canine osteosarcoma, thereby generating potential new targets for therapy to prevent or treat tumor spread in this devastating disease.

This study evaluates a new therapeutic agent designed to inhibit the survivin protein in canine lymphoma.

This study investigates the role of citrullination in canine mammary cancer and how interfering with this process might lead to more effective anticancer treatments.